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1

Drug transporters in the human blood-placental barrier

Kirsi Vähäkangas, Päivi Myllynen

Journal:

British Journal of Pharmacology

Year:

2009

Language:

english

File:

PDF, 282 KB

english, 2009

2

Comparison of in vitro metabolism and cytotoxicity of capsaicin and dihydrocapsaicin

Halme, Mia, Pesonen, Maija, Salo, Heta, Söderström, Martin, Pasanen, Markku, Vähäkangas, Kirsi, Vanninen, Paula

Journal:

Journal of Chromatography B

Year:

2016

Language:

english

File:

PDF, 2.04 MB

english, 2016

3

Apoptosis in operated small cell lung carcinoma is inversely related to tumour necrosis and p53 immunoreactivity

Eerola, Anna-Kaisa, Törmänen, Ulla, Rainio, Pekka, Sormunen, Raija, Bloigu, Risto, Vähäkangas, Kirsi, Lehto, Veli-Pekka, Soini, Ylermi, Pääkkö, Paavo

Journal:

The Journal of Pathology

Year:

1997

Language:

english

File:

PDF, 1.65 MB

english, 1997

4

Molecular epidemiology of human cancer risk: gene-environment interactions andp53 mutation spectrum in human lung cancer

Bennett, William P., Hussain, S. Perwez, Vahakangas, Kirsi H., Khan, Mohammed A., Shields, Peter G., Harris, Curtis C.

Journal:

The Journal of Pathology

Year:

1999

Language:

english

File:

PDF, 340 KB

english, 1999

5

Absence of p53 mutations in benign and pre-malignant male genital lesions with over-expressed p53 protein

Katariina Castrén, Kirsi Vähäkangas, Eini Heikkinen, Annamari Ranki

Journal:

International Journal of Cancer

Year:

1998

Language:

english

File:

PDF, 236 KB

english, 1998

6

TP53 mutations in workers exposed to occupational carcinogens

Kirsi Vähäkangas

Journal:

Year:

2003

Language:

english

File:

PDF, 169 KB

english, 2003

7

p53 protein accumulation and the presence of human papillomavirus dna in bronchiolo-alveolar carcinoma correlate with poor prognosis

Kyösti Nuorva, Ylermi Soini, Dia Kamel, Raimo Pöllänen, Risto Bloigu, Kirsi Vähäkangas, Paavo Pääkkö

Journal:

International Journal of Cancer

Year:

1995

Language:

english

File:

PDF, 1.25 MB

english, 1995

8

Comparison of the formation of benzo[a]pyrene diolepoxide-dna adducts in vitro by rat and human microsomes: Evidence for the involvement of p-450IA1 and p-450IA2

Dr Kirsi Vähäkangas, Hannu Raunio, Markku Pasamen, Päivi Sivonen, Sang-Shin Park, Harry V. Gelboin, Olavi Pelkonen

Journal:

Journal of Biochemical and Molecular Toxicology

Year:

1989

Language:

english

File:

PDF, 632 KB

english, 1989

9

Simultaneous determination of acrylamide, its metabolite glycidamide and antipyrine in human placental perfusion fluid and placental tissue by liquid chromatography–electrospray tandem mass spectrometry

Kirsi Annola, Pekka Keski-Rahkonen, Kirsi Vähäkangas, Marko Lehtonen

Journal:

Journal of Chromatography B

Year:

2008

Language:

english

File:

PDF, 728 KB

english, 2008

10

Fumonisin B1-induced apoptosis in neuroblastoma, glioblastoma and hypothalamic cell lines

Helene Stockmann-Juvala, Jonne Naarala, Jarkko Loikkanen, Kirsi Vähäkangas, Kai Savolainen

Journal:

Year:

2006

Language:

english

File:

PDF, 223 KB

english, 2006

11

DNA damage and p53 in RAW264.7 cells induced by the spores of co-cultivated Streptomyces californicus and Stachybotrys chartarum

Piia Penttinen, Marjo Tampio, Jorma Mäki-Paakkanen, Kirsi Vähäkangas, Jukka Pelkonen, Maija-Riitta Hirvonen

Journal:

Year:

2007

Language:

english

File:

PDF, 638 KB

english, 2007

12

Benzo(a)pyrene-Induced Changes in p53 and Related Proteins in Mouse Skin

Raisa Serpi, Kirsi Vähäkangas

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2003

Language:

english

File:

PDF, 99 KB

english, 2003

13

p53 in head and neck cancer: Functional consequences and environmental implications ofTP53mutations

Jenni K Peltonen, Henni M Helppi, Paavo Pääkkö, Taina Turpeenniemi-Hujanen, Kirsi H Vähäkangas

Journal:

Head & Neck Oncology

Year:

2010

Language:

english

File:

PDF, 392 KB

english, 2010

14

SpecificTP53mutations predict aggressive phenotype in head and neck squamous cell carcinoma: a retrospective archival study

Jenni K Peltonen, Kirsi H Vähäkangas, Henni M Helppi, Risto Bloigu, Paavo Pääkkö, Taina Turpeenniemi-Hujanen

Journal:

Head & Neck Oncology

Year:

2011

Language:

english

File:

PDF, 980 KB

english, 2011

15

p53 Immunohistochemistry in malignant fibrous histiocytomas and other mesenchymal tumours

Ylermi Soini, Kirsi Vähäkangas, Kyösti Nuorva, Dia Kamel, David P. Lane, Paavo Pääkkö

Journal:

The Journal of Pathology

Year:

1992

Language:

english

File:

PDF, 474 KB

english, 1992

16

p53 and c-erbB-2 protein expression in adenocarcinomas and epithelial dysplasias of the gall bladder

Dia Kamel, Paavo Pääkkö, Kyösti Nuorva, Kirsi Vähäkangas, Ylermi Soini

Journal:

The Journal of Pathology

Year:

1993

Language:

english

File:

PDF, 524 KB

english, 1993

17

Lowp53protein expression in salivary gland tumours compared with lung carcinomas

Ylermi Soini, Dia Kamel, Kyösti Nuorva, David P. Lane, Kirsi Vähäkangas, Paavo Pääkkö

Journal:

Virchows Archiv

Year:

1992

Language:

english

File:

PDF, 3.72 MB

english, 1992

18

Comparative analysis ofp53protein immunoreactivity in prostatic, lung and breast carcinomas

Ylermi Soini, Paavo Pääkkö, Kyösti Nuorva, Dia Kamel, David P. Lane, Kirsi Vähäkangas

Journal:

Virchows Archiv

Year:

1992

Language:

english

File:

PDF, 1.31 MB

english, 1992

19

Transplacental passage of lamotrigine in a human placental perfusion system in vitro and in maternal and cord blood in vivo

Päivi K. Myllynen, Päivi K. Pienimäki, Kirsi H. Vähäkangas

Journal:

European Journal of Clinical Pharmacology

Year:

2003

Language:

english

File:

PDF, 193 KB

english, 2003

20

BMP-4 expression has prognostic significance in advanced serous ovarian carcinoma and is affected by cisplatin in OVCAR-3 cells

Liisa Laatio, Päivi Myllynen, Raisa Serpi, Jaana Rysä, Mika Ilves, Elisa Lappi-Blanco, Heikki Ruskoaho, Kirsi Vähäkangas, Ulla Puistola

Journal:

Year:

2011

Language:

english

File:

PDF, 403 KB

english, 2011

21

Foetal Exposure to Food and Environmental Carcinogens in Human Beings

Myöhänen Kirsi, Vähäkangas Kirsi

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2012

Language:

english

File:

PDF, 179 KB

english, 2012

22

UV-B Exposure Causes DNA Damage and Changes in Protein Expression in Northern Pike (Esox lucius) Posthatched Embryos

Eeva-Riikka Vehniäinen, Kirsi Vähäkangas, Aimo Oikari

Journal:

Photochemistry and Photobiology

Year:

2012

Language:

english

File:

PDF, 549 KB

english, 2012

23

Cigarette smoking and drug metabolism

Vähäkangas, Kirsi, Pelkonen, Olavi, Sotaniemi, Eero

Journal:

Clinical Pharmacology & Therapeutics

Year:

1983

Language:

english

File:

PDF, 383 KB

english, 1983

24

The DNA binding of benzo[a]pyrene metabolites catalysed by rat lung microsomes in vitro and in isolated perfused rat lung

Kirsi' Vähäkangas, Daniel W. Nebert, Olavi Pelkonen

Journal:

Chemico-Biological Interactions

Year:

1979

Language:

english

File:

PDF, 899 KB

english, 1979

25

Kinetics of gold nanoparticles in the human placenta

Päivi K. Myllynen, Michael J. Loughran, C. Vyvyan Howard, Raija Sormunen, Adrian A. Walsh, Kirsi H. Vähäkangas

Journal:

Reproductive Toxicology

Year:

2008

Language:

english

File:

PDF, 1.64 MB

english, 2008

26

Preliminary interlaboratory comparison of the ex vivo dual human placental perfusion system

Päivi Myllynen, Line Mathiesen, Marc Weimer, Kirsi Annola, Elina Immonen, Vesa Karttunen, Maria Kummu, Thit Juul Mørck, Jeanette Kolstrup Søgaard Nielsen, Lisbeth Ehlert Knudsen, Kirsi Vähäkangas

Journal:

Reproductive Toxicology

Year:

2010

Language:

english

File:

PDF, 610 KB

english, 2010

27

Human placental perfusion method in the assessment of transplacental passage of antiepileptic drugs

Päivi Myllynen, Päivi Pienimäki, Kirsi Vähäkangas

Journal:

Toxicology and Applied Pharmacology

Year:

2005

Language:

english

File:

PDF, 119 KB

english, 2005

28

Special Issue: The Proceedings of the 10th International Congress of Toxicology, Tampere, Finland, July 11–15, 2004. Living in a safe chemical world

Kirsti Husgafvel-Pursiainen, Arja Rautio, Kai Savolainen, Marja Sorsa, Hanna Tähti, Kirsi Vähäkangas, Pauli Ylitalo

Journal:

Toxicology and Applied Pharmacology

Year:

2005

Language:

english

File:

PDF, 52 KB

english, 2005

29

Azidothymidine and cisplatin increase p14ARF expression in OVCAR-3 ovarian cancer cell line

Liisa Vaskivuo, Jaana Rysä, Johanna Koivuperä, Päivi Myllynen, Tommi Vaskivuo, Katerina Chvalova, Raisa Serpi, Eeva-Riitta Savolainen, Ulla Puistola, Kirsi Vähäkangas

Journal:

Toxicology and Applied Pharmacology

Year:

2006

Language:

english

File:

PDF, 460 KB

english, 2006

30

ABCG2/BCRP decreases the transfer of a food-born chemical carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in perfused term human placenta

Päivi Myllynen, Maria Kummu, Tiina Kangas, Mika Ilves, Elina Immonen, Jaana Rysä, Rauna Pirilä, Anni Lastumäki, Kirsi H. Vähäkangas

Journal:

Toxicology and Applied Pharmacology

Year:

2008

Language:

english

File:

PDF, 518 KB

english, 2008

31

Placental transfer of sulindac, sulindac sulfide, and indomethacin in a human placental perfusion model

Eija S. Lampela, Laura H. Nuutinen, Tero I. Ala-Kokko, Riitta M. Parikka, Risto S. Laitinen, Pentti I. Jouppila, Kirsi H. Vähäkangas

Journal:

American Journal of Obstetrics and Gynecology

Year:

1999

Language:

english

File:

PDF, 166 KB

english, 1999

32

Ethical implications of genetic analysis of individual susceptibility to diseases

Kirsi Vähäkangas

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2001

Language:

english

File:

PDF, 70 KB

english, 2001

33

Germ-Line TP53 Mutations in Finnish Cancer Families Exhibiting Features of the Li-Fraumeni Syndrome and Negative for BRCA1 and BRCA2

Pia Huusko, Katariina Castrén, Virpi Launonen, Ylermi Soini, Kati Pääkkönen, Jaakko Leisti, Kirsi Vähäkangas, Robert Winqvist

Journal:

Cancer Genetics and Cytogenetics

Year:

1999

Language:

english

File:

PDF, 2.51 MB

english, 1999

34

3′-azido-3′-deoxythymidine (AZT) transplacental perfusion kinetics and DNA incorporation in normal human placentas perfused with AZT

Ofelia A Olivero, Riitta Parikka, Miriam C Poirier, Kirsi Vähäkangas

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1999

Language:

english

File:

PDF, 198 KB

english, 1999

35

Gene transfer to human placenta ex vivo: A novel application of dual perfusion of human placental cotyledon

Annaleena Heikkilä, Päivi Myllynen, Leea Keski-Nisula, Seppo Heinonen, Kirsi Vähäkangas, Seppo Ylä-Herttuala

Journal:

American Journal of Obstetrics and Gynecology

Year:

2002

Language:

english

File:

PDF, 1.09 MB

english, 2002

36

The Metabolism of Benzo(a)pyrene in Isolated Perfused Lungs from Variously-treated Rats

Kirsi Vähäkangas, Kaisu Nevasaari, Olavi Pelkonen, Niilo T. Kärki

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

1977

Language:

english

File:

PDF, 635 KB

english, 1977

37

Effects of Various in Vitro - inhibitors of Benzo(a)pyrene Metabolism in Isolated Rat Lung Perfusion

Kirsi Vähäkangas, Kaisu Nevasaari, Olavi Pelkonen, Niilo T. Kärki

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

1979

Language:

english

File:

PDF, 553 KB

english, 1979

38

Effects of Cigarette Smoke on Rat Lung and Liver Ornithine Decarboxylase and Aryl Hydrocarbon Hydroxylase Activities and Lung Benzo(a)pyrene Metabolism

Hannu Raunio, Kirsi Vähäkangas, Hannu Saarni, Olavi Pelkonen

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

1983

Language:

english

File:

PDF, 468 KB

english, 1983

39

Involvement of P450 1A1 in Benzo(a)Pyrene but Not in Benzo(a)Pyrene-7,8-Dihydrodiol Activation by 3-Methylcholanthrene-Induced Mouse Liver Microsomes

Nina Bjelogrlic, Renxiu Peng, Sang S. Park, Harry V. Gelboin, Paavo Honkakoski, Olavi Pelkonen, Kirsi Vähäkangas

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

1993

Language:

english

File:

PDF, 669 KB

english, 1993

40

Transfer of Lidocaine and Bupivacaine Across the Isolated Perfused Human Placenta

Tero I. Ala-Kokko, Päivi Pienimäki, Riitta Herva, Arno I. Hollmén, Olavi Pelkonen, Kirsi Vähäkangas

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

1995

Language:

english

File:

PDF, 822 KB

english, 1995

41

p53 immunohistochemical positivity as a prognostic marker in intracranial tumours

YLERMI SOINI, ASKO NIEMELÄ, DIA KAMEL, RIITTA HERVA, RISTO BLOIGU, PAAVO PÄÄKKÖ, KIRSI VÄHÄKANGAS

Journal:

Year:

1994

Language:

english

File:

PDF, 1.08 MB

english, 1994

42

Human papillomavirus DNA and abnormal p53 expression in carcinoma of the urinary bladder

DIA Kamel, PAAVO PÄÄKkÖ, RAIMO PÖLlÄNen, KIRSI VÄHÄKangas, VELI-PEKKA Lehto, YLERMI Soini

Journal:

Year:

1995

Language:

english

File:

PDF, 1.98 MB

english, 1995

43

Glutathione conjugation by isolated lung cells and the isolated, perfused lung : Effect of extracellular glutathione

Janet R. DAWSON, Kirsi VÄHÄKANGAS, Bengt JERNSTRÖM, Peter MOLDÉUS

Journal:

Year:

1984

Language:

english

File:

PDF, 502 KB

english, 1984

44

The Capacity of Liver Microsomes to Form Benzo[a]Pyrene-Diolepoxide-DNA Adducts and Induction of Cytochrome P450 1A in Feral Fish Exposed to Pulp Mill Effluents

Asta Kantoniemi, Kirsi Vähäkangas, Aimo Oikari

Journal:

Ecotoxicology and Environmental Safety

Year:

1996

Language:

english

File:

PDF, 115 KB

english, 1996

45

The effects of harman and norharman on the metabolism of benzo(a)pyrene in isolated perfused rat lung and in rat lung microsomes

Kirsi Vähäkangas, Olavi Pelkonen

Journal:

Biochemical Pharmacology

Year:

1979

Language:

english

File:

PDF, 543 KB

english, 1979

46

Mouse hepatic cytochrome p-450 isozyme induction by 1,4-bis[2-(3,5-dichloropyridyloxy)] benzene, pyrazole, and phenobarbital

Hannu Raunio, Anneli Kojo, Risto Juvonen, Paavo Honkakoski, Päivi Järvinen, Matti A. Lang, Kirsi Vähäkangas, Harry V. Gelboin, Sang-Shin Park, Olavi Pelkonen

Journal:

Biochemical Pharmacology

Year:

1988

Language:

english

File:

PDF, 838 KB

english, 1988

47

Views of midwives about ethical aspects of participation in placental perfusion studies

Arja Halkoaho, Kirsi Vähäkangas, Arja Häggman-Laitila, Anna-Maija Pietilä

Journal:

Year:

2012

Language:

english

File:

PDF, 261 KB

english, 2012

48

Experimental methods to study human transplacental exposure to genotoxic agents

Kirsi Vähäkangas, Päivi Myllynen

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Year:

2006

Language:

english

File:

PDF, 130 KB

english, 2006

49

Characterization of human breast cancer cell lines for the studies on p53 in chemical carcinogenesis

Marjo Huovinen, Jarkko Loikkanen, Päivi Myllynen, Kirsi H. Vähäkangas

Journal:

Toxicology in Vitro

Year:

2011

Language:

english

File:

PDF, 788 KB

english, 2011

50

Placental transfer and DNA binding of benzo(a)pyrene in human placental perfusion

Vesa Karttunen, Päivi Myllynen, Gabriela Prochazka, Olavi Pelkonen, Dan Segerbäck, Kirsi Vähäkangas

Journal:

Toxicology Letters

Year:

2010

Language:

english

File:

PDF, 686 KB

english, 2010

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